Precision medicine experts

What our precision medicine experts do

The work starts from a mechanism rather than a symptom: mitochondrial efficiency, insulin sensitivity and lipid balance in metabolic health, autophagy, genomic stability and telomere integrity in healthy ageing, toxic protein build-up and neuroinflammation in neurodegeneration. A therapeutic protocol is then built around that mechanism and held as protected intellectual property, combining stem cell biology with targeted gene therapy where tissue repair is the object. Protocols go into human trials. Triple Helix Science reports a completed Phase 1 human trial in which dementia progression reversed. Delivery runs through governments, sovereign health systems and research universities.

How they work

Precision medicine experts at the company work from the position that ageing is systemic, so decline in one organ system accelerates decline in the others. That changes what counts as a result: an intervention is judged on cellular energy, brain health and muscle function together, not on the one organ it was aimed at. The standard held to is healthspan, meaning years lived in good physical and cognitive health, rather than lifespan alone. Protocols across all eight therapeutic areas are developed in house and IP-protected, so a partner adopts a defined intervention rather than a research direction.

When to bring them in

Precision medicine experts are commissioned when a health system is carrying an ageing population and a chronic disease burden that reactive symptom management will not hold, and when the intent is to move national standard of care towards predictive, genome-based intervention. That is an institutional commitment: Triple Helix Science partners with governments, sovereign health systems, research universities, sovereign investors and enterprise pharmaceutical organisations, and does not work direct to consumers. The premise of the engagement is that genetic medicine becomes mainstream standard of care at national scale, which is a public health programme rather than a procurement of individual treatments.